CAS number：1346547-00-9 molecular formula：C20H19FN4O2S
GSK583 是一种高效、口服有效的、高选择性的 RIP2 Kinase 抑制剂，其 IC50 值为 5 nM。GSK583 可同时抑制TNF-α 和IL-6 的产生，IC50 值为 200 nM。 GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.
| Chinese alias | 6-(叔丁基磺酰基)-N-(5-氟-1H-吲唑-3-基)喹啉-4-胺 | ||
| English alias | GSK 583 | GSK-2616583A | ||
| CAS number | 1346547-00-9 | molecular formula | C20H19FN4O2S |
| molecular weight | 398.45 g/mol | Exact mass | - |
| PSA | 96.100 Ų | logp | 4.000 |
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