Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 29.34 μM in HepG2 cells. Ginsenoside Rg6 also exhibits apoptosis -inducing effect. In Vitro Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 25.12±1.04 μM in SK-Hep1 cells, consistent with the data from HepG2 cells. Ginsenoside Rg6 exhibits obvious anti-proliferative and apoptosis-inducing effects when it is applied to JK cells in vitro. Ginsenoside Rg6 blocks S arrest in the cell cycle. CCK-8 method shows that after Ginsenoside Rg6 is used, several groups with different concentrations obviously inhibits JK cell proliferation in human lymphocytoma, with evident dose dependency. Based on IC 50 , the median inhibitory concentration of Ginsenoside Rg6 is 83.08 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:NF-κB|25.12 μM (IC|50|, in SK-Hep1 cell)|NF-κB|29.34 μM (IC|50|, in HepG2 cell)|Apoptosis
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Ginsenoside Rg6
CAS number：147419-93-0 molecular formula：C42H70O12
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| Chinese alias | 人参皂苷Rg6 | ||
| English alias | Ginsenoside Rg6 | AKOS037514880 | MFCD25371996 | DTXSID001316941 | HY-N0907 | CHEBI:176312 | SCHEMBL23960301 | MS-31385 | (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(6-methylhept | ||
| CAS number | 147419-93-0 | molecular formula | C42H70O12 |
| molecular weight | 767 g/mol | Exact mass | ≥99% |
| PSA | 199.000 Ų | logp | 4.600 |
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