compound introduction
DB818 是Homeobox A9(HOXA9) 的有效抑制剂。HOXA9是一种调节造血和白血病细胞增殖的转录因子，与急性髓系白血病 (AML) 有关。DB818 抑制 AML 细胞生长，诱导凋亡 (apoptosis)。
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2-(5-{4-[Amino(imino)methyl]phenyl}-2-thienyl)-1H-benzimidazole-6-carboximidamide dihydrochloride
CAS number：790241-43-9 molecular formula：
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 790241-43-9 | molecular formula | |
| molecular weight | 360.400 g/mol | Exact mass | ≥98% |
| PSA | 157.000 Ų | logp | 2.500 |
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