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4-Cyclohexyl-2-[2-nitro-4-(trifluoromethyl)phenyl]sulfanyl-6-oxo-1H-pyrimidine-5-carbonitrile

CAS number:301177-36-6    molecular formula:C18H15F3N4O3S

overview

compound introduction

RH01386 是一种小分子,可以预防内质网应激 (ERS) 引起的 β 细胞功能障碍 (β cell dysfunction) 和死亡,并抑制促凋亡基因的表达。RH01386 恢复 ERS 受损的葡萄糖刺激的胰岛素分泌反应。RH01386 可以用于 2 型糖尿病的相关研究。

Specs

Chinese alias-
English alias-
CAS number301177-36-6molecular formulaC18H15F3N4O3S
molecular weight424.400 g/molExact mass≥99%
PSA136.000 Ųlogp4.600

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