RH01386 是一种小分子,可以预防内质网应激 (ERS) 引起的 β 细胞功能障碍 (β cell dysfunction) 和死亡,并抑制促凋亡基因的表达。RH01386 恢复 ERS 受损的葡萄糖刺激的胰岛素分泌反应。RH01386 可以用于 2 型糖尿病的相关研究。
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4-Cyclohexyl-2-[2-nitro-4-(trifluoromethyl)phenyl]sulfanyl-6-oxo-1H-pyrimidine-5-carbonitrile
CAS number:301177-36-6 molecular formula:C18H15F3N4O3S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 301177-36-6 | molecular formula | C18H15F3N4O3S |
| molecular weight | 424.400 g/mol | Exact mass | ≥99% |
| PSA | 136.000 Ų | logp | 4.600 |
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