compound introduction
复溶：Reconstitute in 20% ACN/H2O. Ac-DEVD-AFC是一种半胱天冬酶 3（caspase 3）的荧光底物。半胱天冬酶 3 是一种蛋白酶，当细胞处于凋亡条件下会被快速激活，并能切割多聚（ADP - 核糖）聚合酶。这种 7 - 酰胺基 - 4 - 三氟甲基香豆素（AFC）衍生物比 7 - 酰胺基 - 4 - 甲基香豆素（AMC）衍生物具有更好的膜通透性。 这是半胱天冬酶 3 的一种荧光底物，其膜通透性优于 7 - 酰胺基 - 4 - 甲基香豆素衍生物。 A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin (AFC) derivative has better membrane permeability than the 7-amido-4-methylcoumarin (AMC) derivative.A fluorogenic substrate for caspase 3; has better membrane permeability than the 7-amido-4-methylcoumarin derivative.
