compound introduction
HZX-02-059 是一种有效的methuosis诱导剂和双靶点PIKfyve/tubulin抑制剂，具有抗癌活性。Methuosis 主要通过干扰细胞内吞作用（Endocytosis）和胞吐作用（Exocytosis）的平衡，形成大量囊泡，引发细胞死亡。HZX-02-059? 还诱导细胞空泡化，促进凋亡，并下调p53通路，抑制PI3K/AKT磷酸化，抑制c-Myc和NF-κB转录。
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Methuosis inducer 1
CAS number：2240205-30-3 molecular formula：
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2240205-30-3 | molecular formula | |
| molecular weight | 487.500 g/mol | Exact mass | ≥99% |
| PSA | 82.700 Ų | logp | 5.500 |
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