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(1R,3R)-RSL3

CAS number:1219810-15-7    molecular formula:C23H21ClN2O5

overview

compound introduction

(1R,3R)-RSL3 is an isomer of RSL3. RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) ( ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.

Specs

Chinese alias-
English alias-
CAS number1219810-15-7molecular formulaC23H21ClN2O5
molecular weight440.88 g/molExact mass≥99%
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