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(3S,5S,6R)-Navtemadlin

CAS number:2459946-14-4    molecular formula:

overview

compound introduction

(3S,5S,6R)-Navtemadlin is the isomer of Navtemadlin , and can be used as an experimental control. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC 50 of 0.6 nM. Navtemadlin binds to MDM2 with a K d of 0.045 nM.

Specs

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CAS number2459946-14-4molecular formula
molecular weight-Exact mass-
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