(3S,5S,6R)-Navtemadlin is the isomer of Navtemadlin , and can be used as an experimental control. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC 50 of 0.6 nM. Navtemadlin binds to MDM2 with a K d of 0.045 nM.
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(3S,5S,6R)-Navtemadlin
CAS number:2459946-14-4 molecular formula:
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| CAS number | 2459946-14-4 | molecular formula | |
| molecular weight | - | Exact mass | - |
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