CAS number：2366272-43-5 molecular formula：C33H40N6O4
(4aS,8aR)-NPD-001 is a potent and allosteric inhibitor of DNMT3A. (4aS,8aR)-NPD-001 inhibits DNMT3A activity by disrupting protein-protein interactions. (4aS,8aR)-NPD-001 induces apoptosis of acute myeloid leukemia (AML) cell lines. (4aS,8aR)-NPD-001 induces differentiation of distinct AML cell lines including cells with mutated DNMT3A R882.
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| English alias | - | ||
| CAS number | 2366272-43-5 | molecular formula | C33H40N6O4 |
| molecular weight | 584.71 g/mol | Exact mass | - |
| PSA | - | logp | - |
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