compound introduction
Aficamten (CK-274) 是一种新型心肌肌球蛋白 (cardiac myosin)抑制剂，IC50 为 1.4 μM。Aficamten 可用于肥厚型心肌病 (HCM) 的研究。
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aficamten
CAS number：2364554-48-1 molecular formula：C18H19N5O2
overview
Specs
| Chinese alias | 阿菲坎滕 | ||
| English alias | B1I77MH6K1 | WHO 11544 | Aficamten | HY-139465 | MS-25122 | Aficamten [USAN:INN] | AKOS040759755 | Aficamten [INN] | CK-274 | Aficamten [USAN] | N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methylpyrazole-4-carboxamide | 1H-Pyrazo | ||
| CAS number | 2364554-48-1 | molecular formula | C18H19N5O2 |
| molecular weight | 337.38 g/mol | Exact mass | - |
| PSA | 85.800 Ų | logp | 2.100 |
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