SB-267268 是一种选择性和非肽性αvβ3和αvβ5整合素拮抗剂,对人αvβ3,猴αvβ3和 人αvβ5 的Ki分别为 0.9,0.5 和 0.7 nM。SB-267268 抑制人和小鼠αvβ3的IC50值为 0.68 和 0.29 nM。SB-267268 降低血管生成和VEGF表达。
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
SB-267268
CAS number:205678-26-8 molecular formula:C22H24F3N3O4
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 205678-26-8 | molecular formula | C22H24F3N3O4 |
| molecular weight | 451.400 g/mol | Exact mass | ≥99% |
| PSA | 91.800 Ų | logp | 3.100 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS





