CAS number：1313730-14-1 molecular formula：C21H21ClF3N3O2.HCl
CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) 是一种高效、特异的 CCR2 拮抗剂，对 CCR2b 的 IC50 值为 180 nM。CCR2 antagonist 4 hydrochloride 对 MCP-1 诱导的趋化作用有较强的抑制作用，其 IC50 为 24 nM。 Product description： CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
| Chinese alias | N-[2-[[((R3)-1-[(4-氯苯基)甲基]-3-吡咯烷基]氨基]-2-氧乙基]-3-(三氟甲基)苯甲酰胺盐酸盐 | CCR2拮抗剂4盐酸盐 | ||
| English alias | N-[2-[[(3R)-1-[(4-Chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride | Teijin compound 1 hydrochloride | ||
| CAS number | 1313730-14-1 | molecular formula | C21H21ClF3N3O2.HCl |
| molecular weight | 476.32 g/mol | Exact mass | ≥99% |
| PSA | 61.400 Ų | logp | - |
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