INCB 3284 dimesylate 是一种有效的,选择性的人 CCR2 拮抗剂,能够抑制单核细胞趋化蛋白 1 与 hCCR2 结合,IC50 值为 3.7 nM。INCB 3284 dimesylate 可用于急性肝功能衰竭的研究。
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INCB 3284 dimesylate
CAS number:887401-93-6 molecular formula:C26H31F3N4O4•2CH4O3S
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| Chinese alias | N-[2-[[((3R)-1-] [反式-4-羟基-4-(6-甲氧基-3-吡啶基)环己基] -3-吡咯烷基]氨基] -2-氧代乙基] -3-(三氟甲基)-苯甲酰胺二甲磺酸盐 | INCB 3284 二甲磺酸盐 | ||
| English alias | N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate | ||
| CAS number | 887401-93-6 | molecular formula | C26H31F3N4O4•2CH4O3S |
| molecular weight | 712.76 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 229.000 Ų | logp | - |
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