CY-09 是一种选择性和直接的 NLRP3 抑制剂。CY-09 直接与 NLRP3 NACHT 结构域的 ATP 结合基序结合,抑制 NLRP3 ATP酶活性,从而抑制 NLRP3 炎症小体的组装和活化。
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CY 09
CAS number:1073612-91-5 molecular formula:C19H12F3NO3S2
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| Chinese alias | 4-[[4-Oxo-2-thioxo-3-[[3-(三氟甲基)苯基]甲基] -5-噻唑烷亚叉基]甲基]苯甲酸 | ||
| English alias | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid | 4-4-Oxo-2-thioxo-3-3-(trifluoromethyl)phenylmethyl-5-thiazolidinylidenemethylbenzoic acid | (E)-4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)benzyl)thiazolidin | ||
| CAS number | 1073612-91-5 | molecular formula | C19H12F3NO3S2 |
| molecular weight | 423.43 g/mol | Exact mass | - |
| PSA | 115.000 Ų | logp | 4.900 |
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