Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA, an orphan agent, is a specific ligand of NOD2 used as an ins Appearance:Solid IC50& Target:NOD2 In Vitro:Mifamurtide TFA (MTP-PE TFA; 100 µM) induces a reduction of MG63 cells number when co-cultured with macrophages. Mifamurtide TFA (100 µM) increases both the M1 polarization marker iNOS and the M2 polarization marker CD206 mRNAs; both pro-inflammatory In Vivo:Mifamurtide TFA (MTP-PE TFA; 1mg/kg; i.v.; twice per week for 4 weeks) causes a trend of diminished spontaneous lung metastasis dissemination. Mifamurtide TFA (50 μg/mouse) improves glucose tolerance during endotoxemia in mice. Mifamurtide TFA (equi Biological Activity:Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA, an orphan agent, is a specific ligand of NOD2 used as an ins
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Mifamurtide TFA
CAS number：unknown molecular formula：C61H110F3N6O21P
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| Chinese alias | 米法莫替丁 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C61H110F3N6O21P |
| molecular weight | 1351.52 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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