CAS number：1000279-69-5 molecular formula：C20H19ClN2O3S
A-867744是α7 nAChRs的阳性变构调节剂，在非洲爪蟾卵细胞中对人和鼠的α7受体ACh激发的电流IC50分别为0.98 和1.12 μM。 A-867744 is a positive allosteric modulator of α7 nAChRs (IC50 values are 0.98 and 1.12 μM for human and rat α7 receptor ACh-evoked currents respectively, in X. laevis oocytes). Displays no activity at 5-HT3A, α3β4 or α4β2 nAChRs.
| Chinese alias | - | ||
| English alias | 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide | 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)-benzenesulfonamide | GTPL3986 | Benzenesulfonamide, 4-(5-(4-chlorophenyl)-2-methyl-3-(1-oxopropyl)-1H-pyrrol-1-yl)- | | ||
| CAS number | 1000279-69-5 | molecular formula | C20H19ClN2O3S |
| molecular weight | 402.89 g/mol | Exact mass | - |
| PSA | 90.500 Ų | logp | 3.700 |
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