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Cryptopleurine

CAS number:482-22-4    molecular formula:

overview

compound introduction

(–)-Cryptopleurine 是一种存在于樟科植物中的生物碱,具有多种生物活性。它可抑制人类 A375 黑色素瘤、A431 表皮样癌、A549 肺癌、MES-SA 子宫肉瘤和 MCF-7 乳腺癌细胞的生长(所有细胞的IC50=3 nM)。(–)-Cryptopleurine 可在缺氧反应元件 (HRE) 报告基因检测中抑制缺氧诱导的基因表达(IC50=8.7 nM)。(–)-Cryptopleurine (500 μg/ml) 可防止感染烟草花叶病毒 (TMV) 的烟草 (N. tabacum) 植物形成病变。它还可抑制酵母和哺乳动物核糖体的蛋白质合成。

Specs

Chinese alias-
English alias-
CAS number482-22-4molecular formula
molecular weight377.500 g/molExact mass-
PSA30.900 Ųlogp5.100

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