异硫氰酸荧光素标记的鬼笔环肽可用于：观察内皮素-1（ET-1）和血管紧张素II（Ang-II）处理后原代乳鼠心肌细胞（PNCM）和H9C2细胞（大鼠心肌成肌细胞）F-肌动蛋白的重组情况。在免疫化学中标记微丝。在免疫荧光分析中对F-肌动蛋白进行染色。应用： 鬼笔环肽是由死亡之帽鬼笔鹅膏产生的鬼笔毒素。它是一种可与肌动蛋白相互作用的环肽，最早是在鬼笔环肽中毒的大鼠体内发现的。它是一种七肽，本质上是环状的，在6位色氨酸和3位半胱氨酸之间具有交联键。鬼笔环肽中氨基酸7（γ-δ-二羟基亮氨酸）的侧链可被修饰，通过该修饰可以产生荧光标记的鬼笔环肽化合物。 Phalloidin is a phallotoxin produced by death cap mushroom Amanita phalloides . It is a cyclic peptide, which interacts with actin and this was first identified in phalloidin-poisoned rats. It is a heptapeptide, cyclic in nature, with a crosslink between tryptophan at position 6 and cysteine at position 3. The side chain of amino acid 7 (γ-δ-dihydroxyleucine) in phalloidin, is accessible to modifications, through which fluorescently labelled phalloidin compounds can be produced. Application: Phalloidin, Fluorescein Isothiocyanate Labeled has been used: To visualize F-Actin reorganization in primary neonatal cardiomyocytes (PNCMs) and H9C2 cells (rat cardiac myoblasts) following endothelin-1 (ET-1) and angiotensin II (Ang II) treatment. In immunochemistry to label microfilament. In immunofluorescence analysis to stain F-actin.
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鬼笔环肽，异硫氰酸荧光素标记
CAS number：unknown molecular formula：
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | sequence Amanita pha |
| PSA | - | logp | - |
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