RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase IC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)
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RIPK1-IN-4
CAS number:1481641-08-0(DMSO) molecular formula:C23H23N5O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1481641-08-0(DMSO) | molecular formula | C23H23N5O2 |
| molecular weight | 401.46 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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