compound introduction
Pentiapine (CGS 10746) is a dopamine release inhibitor without binding to synaptic dopamine receptor sites In Vivo Pentiapine is a novel dopamine release inhibitor.The results show that Pentiapine dose-dependently reduces motor activity of mice. Moreover, Pentiapine dose-dependently reduces morphine-induced hyperactivity. Newman-Keuls post-hoc comparisons indicate that the group receiving morphine plus saline presents more activity than the groups receiving morphine plus 2 (P Form:Solid IC50& Target:Dopamine receptor
