CAS number：2935964-98-8 molecular formula：C20H18FN3O2S
TNG260 is a CoREST-selective deacetylase ( CoreDAC ) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3 . TNG260 leads to HDAC1 inhibition, reverses anti-PD1 resistance driven by loss of STK11. TNG260 decreases intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killing IC50& Target:HDAC1 HDAC3
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| English alias | - | ||
| CAS number | 2935964-98-8 | molecular formula | C20H18FN3O2S |
| molecular weight | 383.44 g/mol | Exact mass | - |
| PSA | - | logp | - |
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