compound introduction
Selepressin (FE 202158) acetate 是一种选择性的加压素 V1A 受体 (vasopressin V1A receptor) 激动剂。Selepressin acetate 是一种有效的血管加压素。Selepressin acetate 可用于脓毒性休克的研究。 Appearance:Solid In Vitro:Selepressin acetate (100 nM, 48 or 72 h) ameliorates thrombin or VEGF-induced HLMVECs barrier dysfunction. Selepressin acetate (1-1000 nM, 72 h) prevents the LPS-Induced loss of VE-cadherin and cortical actin in HLMVECs. Selepressin acetate (100 In Vivo:Selepressin acetate (1 μg/kg/min, left jugular vein infusion for 12 min) increases 38.5% of the mean arterial pressure (MAP) in LPS-induced, fluid-resuscitated rabbit endotoxemia model. Selepressin acetate (7 pmol/kg/min, 10 μL/min, i.v. infusion) bl
