Bifluranol (BX341) is an anti-androgen. In Vivo The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [ 3 H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3 H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL -1 (rat) or 1 ng Bifluranol equivalents mL -1 (ferret) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Androgen Receptor
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Bifluranol
CAS number：34633-34-6 molecular formula：C17H18F2O2
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| Chinese alias | 双氟醇 | ||
| English alias | erythro-2,3-Bis(3-fluor-4-hydroxyphenyl)pentan | HY-U00229 | DTXSID30865725 | Q27259015 | AKOS040741492 | Bifluranolum [INN-Latin] | (2S,3R)-bifluranol | SCHEMBL131387 | Bifluranol [INN:BAN] | 4,4'-(2S,3R)-pentane-2,3-diylbis(2-fluorophenol) | Bifluranolu | ||
| CAS number | 34633-34-6 | molecular formula | C17H18F2O2 |
| molecular weight | 292.32 g/mol | Exact mass | ≥98% |
| PSA | 40.500 Ų | logp | 4.800 |
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