compound introduction
MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor. Appearance:Solid IC50& Target:SIRT5 In Vitro:MC3482 inhibits sirtuin5. 50 μM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-over Biological Activity:MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor.
