Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1 , HCMV, influenza virus , and HIV-1 . Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure In Vitro Soyasaponin II inhibits the replication of HSV-1 (IC 50 =54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Soyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:HSV-1|54 μM (IC|50|)|HIV-1|112 μM (IC|50|)|influenza virus|88 μM (IC|50|)|HCMV|104 μM (IC|50|)|NLRP3 inflammasome
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Soyasaponin II
CAS number：55319-36-3 molecular formula：C47H76O17
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| Chinese alias | 大豆皂苷Ⅱ | ||
| English alias | HY-122920 | Q27110224 | AKOS040760720 | DTXSID801317250 | C12081 | SCHEMBL14693925 | (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9S,12aR,14aS,14bR)-9-hydro xy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8 ,9,10,12,12a,14,14a-tetradec | ||
| CAS number | 55319-36-3 | molecular formula | C47H76O17 |
| molecular weight | 913.10 g/mol | Exact mass | ≥99% |
| PSA | 275.000 Ų | logp | 2.400 |
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