GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist In Vivo GDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor regression in estrogen receptor (ER)+breast cancer (BC) patient-derived xenograft models . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Estrogen receptor
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GDC-0927
CAS number:1642297-01-5 molecular formula:C28H28FNO4
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| Chinese alias | - | ||
| English alias | GDC-0927 free base | HY-111484 | BG166429 | BS-16112 | SCHEMBL16325181 | US10227334, Example 3 | BCP29507 | Q50825069 | GDC 0927 | NSC-812902 | GDC0927 | GDC-0927 | 1642297-01-5 (free base) | 1-PIPERIDINEETHANOL, 4-HYDROXY-.ALPHA.-(4-HYDROXYPHENYL)-.BETA. | ||
| CAS number | 1642297-01-5 | molecular formula | C28H28FNO4 |
| molecular weight | 461.5 g/mol | Exact mass | ≥99% |
| PSA | 62.200 Ų | logp | 4.700 |
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