Itraconazole-d 9 is the deuterium labeled Itraconazole.Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor. In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Itraconazole-d9
CAS number：1309272-50-1 molecular formula：C35H29D9Cl2N8O4
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| Chinese alias | 伊曲康唑-d9 | ||
| English alias | - | ||
| CAS number | 1309272-50-1 | molecular formula | C35H29D9Cl2N8O4 |
| molecular weight | 714.69 g/mol | Exact mass | - |
| PSA | - | logp | - |
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