compound introduction
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction ( IC 50 =25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 ( K d =15 nM) than YAP (50-171) ( K d = 40 nM) In Vitro YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K d of His-YAP(1209-426) is determined to be 40 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 25 nM (YAP-TEAD interaction)
