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[Asp5]-Oxytocin

CAS number:65907-78-0    molecular formula:C43H65N11O13S2

overview

compound introduction

[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg 2+. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic. In Vitro [Asp5]-Oxytocin retains not only a high affinity for the uterotonic receptor, but also an intrinsic activity identical with that of oxytocin. [Asp5]-Oxytocin displays an increasing intrinsic activity enhanced by 1 mM Mg 2+. [Asp5]-Oxytocin exerts the same potencies of rat uterotonic, avian vasodepressor, and rat antidiuretic with 20.3, 41, and 0.14 units/mg dose. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias[Asp5]-催产素
English alias-
CAS number65907-78-0molecular formulaC43H65N11O13S2
molecular weight1008.17 g/molExact mass≥99%
PSA-logp-

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