CAS number：1449746-00-2 molecular formula：C17H16ClFN2O2
盐酸美呋哌瑞是一种底物竞争性和选择性的 PARP1/2 抑制剂，IC50 分别为 3.2 nM 和 1.9 nM。盐酸美呋哌瑞诱导细胞凋亡 (apoptosis)，并在体内外具有显着的抗癌活性。 Mefuparib hydrochloride is a substrate-competitive and selective PARP1/2 inhibitor with IC50s of 3.2 nM and 1.9 nM, respectively. Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo.
| Chinese alias | - | ||
| English alias | Mefuparib (hydrochloride) | 82IYE3T3BE | CVL-218 | MPH | hydrochloride | 5-fluoro-2-[4-(methylaminomethyl)phenyl]-1-benzofuran-7-carboxamide | ||
| CAS number | 1449746-00-2 | molecular formula | C17H16ClFN2O2 |
| molecular weight | 334.77 g/mol | Exact mass | ≥98% |
| PSA | 68.300 Ų | logp | - |
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