DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver damage. Form:Solid
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DI-1859
CAS number:2247061-09-0 molecular formula:C30H45N5O3S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2247061-09-0 | molecular formula | C30H45N5O3S |
| molecular weight | 555.78 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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