SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer In Vitro SEMBL inhibits MMP-2 expression and cellular metastatic activity in ovarian carcinoma cells. SEMBL inhibits the cell-free DNA binding of NF-κB in the ES-2 nuclear extract and inhibits the constitutively activated NF-κB activity in ovarian carcinoma cells. SEMBL inhibits cellular migration, invasion and MMP-2 expression in ovarian carcinoma cells at non-toxic concentrations. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:NF-κB, MMP-2
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SEMBL
CAS number：1443448-82-5 molecular formula：C12H11NO4
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1443448-82-5 | molecular formula | C12H11NO4 |
| molecular weight | 233.22 g/mol | Exact mass | ≥97% |
| PSA | 75.600 Ų | logp | 1.500 |
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