compound introduction
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a K i of 4000 nM at the dopamine D 2 receptor In Vivo Administration of Sigma-LIGAND-1 hydrochloride reverseS amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 hydrochloride and its structural analogues have the potential antipsychotic activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 16 nM (DTG site of sigma receptor), 19 nM (PPP site of sigma receptor), Ki: 4000 nM (Dopamine D2 receptor)
