CAS number：2775311-17-4 molecular formula：C22H23F4N5O
GFB-12811 is a high selective and orally active CDK5 inhibitor with an IC 50 of 2.3 nM. GFB-12811 is highly selective over the other tested kinases (CDK1/2/6/7/9) Form:Solid IC50& Target:Cdk5/p25 2.3 nM (IC 50 ) CDK2/CycA 211 nM (IC 50 ) CDK7/Cyclin H/MAT1 718 nM (IC 50 ) CDK9/CycT1 894 nM (IC 50 )
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| CAS number | 2775311-17-4 | molecular formula | C22H23F4N5O |
| molecular weight | 449.44 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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