compound introduction
TP0597850 is a selective inhibitor of MMP2 ( IC 50 =0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t 1/2 =265 min) In Vitro TP0597850 (compound 18) exhibits extremely high chemical stability under a wide range of pH conditions. TP0597850 shows an inhibition constant against MMP2 with a Ki value of 0.034 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:MMP2 0.22 nM (IC 50 ) MMP-12 250 nM (IC 50 ) MMP13 240 nM (IC 50 )
