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1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt

Dangerous Goods

CAS number:67254-28-8    molecular formula:C42H78O10PNa

overview

compound introduction

磷酸甘油 (PG) 也称为甘油磷脂。是膜双层的重要组成部分。它具有甘油的三碳骨架,两个长链脂肪酸,酯化成甘油的碳 1 和碳 2 上的羟基,以及酯化成甘油的 C3 羟基的磷酸。 在所有细胞的膜中发现高水平含量,在脂肪储存中发现低水平含量。 1,2-二油酰- 锡 -甘油-3-磷酸-(1′-外消旋甘油)(DOPG)/18:1(Δ9-顺)PG 在其头基上有两个羟基。是一种阴离子脂质。 应用: 18:1(Δ9-Cis)PG 已被用于: 制备巨大单层膜囊泡 (GUV) 制备 200 nm 大单层膜囊泡 ( LUV ) 作为天然巨噬细胞膜的补充,生成带有人工修饰电荷的膜脂质体 生化/生理作用:磷酸甘油 (PG)/甘油磷脂在细胞信号传导系统中起关键作用。也充当细胞膜中蛋白质的锚。 The lipid DOPG has significant influence on multidrug transport. The DOPG membrane content can alter substrate transport of small multidrug transporters (SMR) proteins by an order of magnitude.

Specs

Chinese alias18:1 (Δ9-Cis) PG | L-α-Phosphatidyl-DL-glycerol, dioleoyl sodium salt | L-α-Phosphatidyl-DL-glycerol, dioleoyl
English alias(9Z)-9-Octadecenoic acid 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt | 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt | DOPG-Na | PG(18:1(9Z)/18:1(9Z)) | DOPG-Na, r- | 1,2-di-(9
CAS number67254-28-8molecular formulaC42H78O10PNa
molecular weight797.03 g/molExact mass≥99%
PSA152.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3
Personal protective equipment:
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

Found 1 shareMSDS
Chloroform solution of 1,2-dioleyl-SN-glyceryl-3-phosphate-RAC-glycerol sodium salt | 2-dioleoyl-sn-glycero-3-phospho- (1 '-rac-glycerol) (sodium salt)