干扰素(IFN)以其在宿主防御机制中的关键作用而闻名。Ⅰ型干扰素包括IFN-alpha 家族,IFN-beta, -omega,-kappa 和 Limitin/IFN-zeta,对调节病毒感染的免疫应答具有重要意义。Ⅱ型干扰素组仅包括干扰素γ。IFN-γ是一种多功能细胞因子,具有抗增殖、免疫调节和促炎症作用,对免疫应答的许多方面都很重要。Ⅲ型干扰素家族包括IL-29/IFN-lambda 1, IL-28A/IFN-lambda 2, IL-28B/IFN-lambda 3, and IFN-lambda 4。与Ⅰ型干扰素类似,Ⅲ型干扰素具有抗病毒、抗增殖和免疫调节作用。 IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
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Recombinant Human IFN-alpha-2B Protein
CAS number:unknown molecular formula:
overview
compound introduction
Specs
| Chinese alias | 重组人 IFN-alpha-2B 蛋白 | ||
| English alias | IFN-alpha-2 | Interferon alpha-A | LeIF A | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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