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PROTAC IRAK4 degrader-1

CAS number:2360533-90-8    molecular formula:C44H39F3N12O7

overview

compound introduction

PROTAC IRAK4 degrader-1 is a Cereblon -based PROTAC interleukin-1 receptor-associated kinase 4 ( IRAK4 ) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively Form:Solid IC50& Target:IRAK4 Cereblon

Specs

Chinese aliasPROTAC IRAK4 降解剂-1
English alias-
CAS number2360533-90-8molecular formulaC44H39F3N12O7
molecular weight904.85 g/molExact mass≥99%
PSA-logp-

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