CAS number：798577-91-0 molecular formula：C20H17N7O2
Avanbulin (BAL27862) 是一种有效的秋水仙碱位点结合的微管蛋白 (tubulin) 装配抑制剂。Avanbulin 在 37 °C 抑制微管蛋白组装 (IC50=1.4 μM)。Avanbulin 与微管蛋白结合的 Kd 值为 244 nM。Avanbulin 可用于癌症和细胞分裂的研究 Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC50 of 1.
| Chinese alias | - | ||
| English alias | 3-((4-(1-(2-(4-Aminophenyl)-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-yl)amino)propanenitrile | BAL27862 | BAL-27862 | Avanbulin [INN] | Avanbulin | Avanbulin [USAN] | Y7KSX9YI58 | ||
| CAS number | 798577-91-0 | molecular formula | C20H17N7O2 |
| molecular weight | 387.39 g/mol | Exact mass | ≥97% |
| PSA | 136.000 Ų | logp | 2.400 |
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