CAS number：162112-37-0 molecular formula：C18H17F3N4O2S
RWJ 50271 是一种选择性的，具有口服活性的 LFA-1/ICAM-1 相互作用抑制剂，IC50 值为 5.0 μM (HL60 cells)。RWJ 50271 抑制 LFA-1/ICAM-1 介导的细胞粘附。 RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion.
| Chinese alias | N-(3-羟丙基)-5-甲基-1-[-4-[3-(三氟甲基)苯基)]-2-噻唑基] -1H-吡唑-4-羧酰胺 | ||
| English alias | N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide | ||
| CAS number | 162112-37-0 | molecular formula | C18H17F3N4O2S |
| molecular weight | 410.41 g/mol | Exact mass | ≥97% |
| PSA | 108.000 Ų | logp | 3.200 |
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