OB-24 是血红素加氧酶-1 (HO-1) 的有效抑制剂。血红素加氧酶 1 是热休克蛋白家族的成员,作为氧化应激的传感器和调节剂发挥着关键作用。OB-24 显着抑制体外细胞增殖和体内肿瘤生长和淋巴结/肺转移。OB-24 具有研究晚期前列腺癌 (PCA) 的潜力。 OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA).
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OB 24 hydrochloride
CAS number:939825-12-4 molecular formula:C15H17BrN2O2.HCl
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compound introduction
Specs
| Chinese alias | 1-[[2-[2-(4-溴苯基)乙基] -1,3-二氧戊环-2-基]甲基] -1H-咪唑盐酸盐 | ||
| English alias | SCHEMBL407935 | UNII-B2FQJ9RF5L | 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride | 1H-Imidazole, 1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-, hydrochloride (1:1) | 2-(2-(4-Bromophenyl)ethyl)-2-((1H-imidaz | ||
| CAS number | 939825-12-4 | molecular formula | C15H17BrN2O2.HCl |
| molecular weight | 373.67 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 36.300 Ų | logp | - |
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