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NF 1819

CAS number:1881244-28-5    molecular formula:C24H22FN5O4

overview

compound introduction

MGL-IN-1 是一种高效、选择性的不可逆 MGL (β-内酰胺基单酰甘油脂肪酶)抑制剂。MGL-IN-1 在体内多发性硬化症模型中缓解疾病症状,在体内急性炎性疼痛模型中表现出镇痛作用。MGL-IN-1 具有较高的膜通透性和血脑屏障通透性。

Specs

Chinese alias(3R,4S)-rel-4-(1,3-苯并二恶唑-5-基)-3-(4-氟苯基)-1-[1-(1H)-1,2,4-三唑-1-羰基)-4-哌啶基] -2-氮杂环丁酮
English alias(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone | NF-1819 | NF1819 | MGL-IN-1
CAS number1881244-28-5molecular formulaC24H22FN5O4
molecular weight463.46 g/molExact mass≥98%(HPLC)
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