CC0651 是一种人Cdc34泛素结合酶变构抑制剂。CC0651 有效抑制 p27Kip1的泛素化,IC50 为 1.72 μM。 CC0651 is an allosteric inhibitor of human Cdc34 ubiquitin binding enzyme. CC0651 inhibited ubiquitination of p27Kip1 with IC50 of 1.72 μM.
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CC 0651
CAS number:1319207-44-7 molecular formula:C20H21Cl2NO6
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compound introduction
Specs
| Chinese alias | (2R,3S,4S)-5-[4-(3,5-二氯苯基)苯基] -2,3-二羟基-4-(2-甲氧基乙酰胺基)戊酸 | ||
| English alias | (2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid | ||
| CAS number | 1319207-44-7 | molecular formula | C20H21Cl2NO6 |
| molecular weight | 442.29 g/mol | Exact mass | ≥95% |
| PSA | 116.000 Ų | logp | 2.700 |
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