CAS number：2117404-84-7 molecular formula：C20H15F3N4O2
BAY-677 是BAY-678 的无活性阴性对照。BAY-678 是具有、高效的、选择性的、人中性粒细胞弹性蛋白酶 (HNE) 的细胞渗透性抑制剂，其 IC50 值为 20 nM。BAY-678 也是被基因结构组学联盟 (SGC) 推荐的化学探针。 BAY-677 is an inactive control for BAY-678. BAY-678 is an highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM[1] and it is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
| Chinese alias | 5-[(4S)-5-乙酰基-1,2,3,4-四氢-6-甲基-2-氧代-1-[3-(三氟甲基)苯基] -4-嘧啶基] -2-吡啶腈 | 海湾 677 | ||
| English alias | 2117404-84-7 | NCGC00481106-01 | 9RWG27AN5N | 5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile | AKOS034831615 | SCHEMBL4179543 | UNII-9RWG27AN5N | 5-((4S)-5-Acetyl-6-methyl-2-oxo-1-(3- | ||
| CAS number | 2117404-84-7 | molecular formula | C20H15F3N4O2 |
| molecular weight | 400.35 g/mol | Exact mass | ≥98% |
| PSA | 86.100 Ų | logp | 2.500 |
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