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AS2717638

CAS number:2148339-28-8(DMSO)    molecular formula:C25H25N3O5

overview

compound introduction

AS2717638 是一种具有口服生物活性的,选择性的溶血磷脂酸受体5 (LPA5) 的拮抗剂,其对 hLPA4 的 IC50值为38 nM。AS2717638 还能显著改善 PGE2、PGF2α以及 AMPA 诱导的异位疼痛。 AS2717638 is an oral active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC 50 of 38 nM for hLPA5. AS2717638 also significantly improves PGE 2 -, PGF 2α -, and AMPA-induced allodynia IC50& Target:IC50: 38 nM (hLPA5)

Specs

Chinese alias-
English alias-
CAS number2148339-28-8(DMSO)molecular formulaC25H25N3O5
molecular weight447.48 g/molExact mass-
PSA-logp-

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