Tebanicline hydrochloride (Ebanicline hydrochloride) 是 nAChR 的调节剂,具有有效的口服止痛活性。Tebanicline hydrochloride 抑制 cytisine 与神经元 nAChR 的结合的 Ki 值为 37 pM。 Tebanicline hydrochloride (Ebanicline hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. Tebanicline hydrochloride inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM.
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ABT 594 hydrochloride
CAS number:203564-54-9 molecular formula:C9H11ClN2O•HCL
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compound introduction
Specs
| Chinese alias | (R)-5-(氮杂环丁烷-2-基甲氧基)-2-氯吡啶盐酸盐 | 替巴克兰盐酸盐 | ||
| English alias | Q27259178 | P18225 | Tebanicline(hydrochloride) | Ebanicline hydrochloride | 48U2WUT775 | Tebanicline (hydrochloride) | 5-[[(2R)-azetidin-2-yl]methoxy]-2-chloropyridine;hydrochloride | Tebanicline hydrochloride | ABT 594 hydrochloride | 203564-54-9 (HCl) | ||
| CAS number | 203564-54-9 | molecular formula | C9H11ClN2O•HCL |
| molecular weight | 235.11 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 34.200 Ų | logp | - |
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