compound introduction
ICA 110381 (Compound 16) 是一种用于治疗癫痫病的 KCNQ2/Q3 potassium channel 的开启剂。ICA 110381表现出针对 KCNQ2/Q3 的激动剂活性，其EC50值为0.38 μM，和对 KCNQ1 的拮抗剂活性，其IC50值为15 μM。
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ICA 110381
CAS number：325457-99-6 molecular formula：C12H8Cl2N2O
overview
Specs
| Chinese alias | 4-氯-N-(6-氯-3-吡啶基)苯甲酰胺 | ||
| English alias | - | ||
| CAS number | 325457-99-6 | molecular formula | C12H8Cl2N2O |
| molecular weight | 267.11 g/mol | Exact mass | 10mM in DMSO |
| PSA | 42.000 Ų | logp | 3.300 |
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