compound introduction
Yoda1是人源和小鼠源Piezo1的激动剂。小鼠源EC50为17.1 μM，人源EC50为26.6 μM。 在没有其他细胞成分的情况下，Yoda1可激活纯化的Piezo1通道。
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Yoda 1
CAS number：448947-81-7 molecular formula：C13H8Cl2N4S2
overview
Specs
| Chinese alias | 2-[5-[[((2,6-二氯苯基)甲基]硫代] -1,3,4-噻二唑-2-基]吡嗪 | ||
| English alias | GTPL9817 | s6678 | UNII-TW6GF9RW6S | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine | 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine | 2-[5-(2,6-Dichloro-benzylsulfanyl)-[1,3,4]thiadiazol-2-yl]-pyrazine | N | ||
| CAS number | 448947-81-7 | molecular formula | C13H8Cl2N4S2 |
| molecular weight | 355.27 g/mol | Exact mass | - |
| PSA | 105.000 Ų | logp | 3.500 |
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