CAS number：870677-05-7 molecular formula：C17H27NO3
DMAPT (Dimethylamino Parthenolide) 是一种NF-κB 抑制剂，是一种 Parthenolide (PTL) 的类似物，对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。 DMAPT (Dimethylamino Parthenolide) is an NF-κB inhibitor and a Parthenolide (PTL) analogue with an LD50 value of 1.7 μM for primary acute myeloid leukemia cells. It has potential anti-tumor and anti-metastatic effects.
| Chinese alias | (1aR,4E,7aS,8R,10aS,10bS)-8-[((二甲基氨基)甲基]-2,3,6,7,7a,8,10a,10b-八氢-1a,5-二甲基-氧杂壬酸[9,10]环癸[1,2-b]呋喃-9(1aH)-酮 | 8-[(二甲氨基)甲基]-八氢-1a,5-二甲基氧苯并[9,10]环癸[1,2-b]呋喃-9(1aH)-酮 | ||
| English alias | (S)-DMAPT | HY-16172 | DMAPT | (1S,2R,4R,7Z,11S,12S)-12-[(dimethylamino)methyl]-4,8-dimethyl-3,14-dioxatricyclo[9.3.0.0?,?]tetradec-7-en-13-one | NSC-734325 | LC-1 | (1S,2R,4R,7Z,11S,12S)-12-[(dimethylamino)methyl]-4,8-dimethyl-3,14-dioxatricyclo[9.3.0.02 | ||
| CAS number | 870677-05-7 | molecular formula | C17H27NO3 |
| molecular weight | 293.41 g/mol | Exact mass | - |
| PSA | 42.100 Ų | logp | 1.900 |
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