CAS number：956905-27-4 molecular formula：C19H16N8O
PF-04217903是一种选择性的，ATP竞争性c-Met抑制剂，IC50为4.8 nM，对致癌基因突变型敏感(对Y1230C突变型没有活性)。A selective ATP-competitive Met inhibitor. PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant). A selective ATP-competitive Met inhibitor.
| Chinese alias | - | ||
| English alias | 2-(4-(3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-1H-pyrazol-1-yl)ethanol | 2-[4-[1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazol-1-yl]ethanol | HY-12017 | PF-4217903 | AC-35476 | AKOS040732470 | MFCD12407410 | | ||
| CAS number | 956905-27-4 | molecular formula | C19H16N8O |
| molecular weight | 372.38 g/mol | Exact mass | ≥98% |
| PSA | 107.000 Ų | logp | 0.7 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
